Antibodies that bind peptidoglycan recognition protein 1

• 收藏
• 分享

专利权人:

Novo Nordisk A/S

发明人:

Vibeke Westphal Stennicke,Christine Brender Read,Joseph Leon Kuijper,Xiaoting Tang,Mark Heipel,Siv Annegrethe Hjorth

申请号：

US15483390

公开号：

US10150809B2

申请日:

2017.04.10

申请国别(地区):

US

年份:

2018

代理人:

摘要：

Disclosed herein is a method for identifying TREM-1's ligand and antibodies, or fragments thereof, which are capable of modifying the function of TREM-1's ligand. Antibodies that reduce or block TREM-1 activation may be identified and selected using this method. Antibodies that bind to TREM-1's ligand and reduce TREM-1 activity may be suitable for use as medicaments.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/