METHOD FOR PREPARATION OF RANOLAZINE

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专利权人:

SHANGHAI KUOIKEE LABORATORIES CO.; LTD

发明人:

SHI, MINGFENG,LI, DAN,XU, LING

申请号：

EP10853535

公开号：

EP2586774A4

申请日:

2010.12.02

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

A process for the preparation of ranolazine comprises the step of condensing N-(2,6-dimethylphenyl)-1-piperazinyl acetamide with a compound of formula (I) to obtain ranolazine, in which X is chlorine or bromine. Ranolazine is prepared by condensing ring-opening halide which replaces epoxide in this process.

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中国工程科技知识中心

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http://www.ckcest.cn/home/