ALEXANDER KIRSCHENBAUM,ALICE C. LEVINE,STEVEN L. REGEN,VACLAV JANOUT
申请号：
US14055313
公开号：
US20140045797A1
申请日:
2013.10.16
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention concerns conjugate compounds comprising a bisphosphonate covalently bonded to a prostatic acid phosphatase inhibitor and compositions comprising such conjugates. Methods for treating and inhibiting prostate cancer bone metastases, and determining whether a conjugate is useful for such treatment are also provided. In some instances, the bisphosphonate is alendronate, and it is covalently bonded to either tartaric acid or glyceric acid.
