Robert Hershberg;Brad Newhouse;James Jeffry Howbert;Hong Woon Yang;Laurence E. Burgess;Gregory Dietsch;Joseph P. Lyssikatos
发明人:
James Jeffry Howbert,Gregory Dietsch,Robert Hershberg,Laurence E. Burgess,Joseph P. Lyssikatos,Brad Newhouse,Hong Woon Yang
申请号:
US12859178
公开号:
US08691809B2
申请日:
2010.08.18
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, infectious disease, inflammatory disorder, graft rejection, and graft-verses-host disease.