CHO, MYUNG-SAM,CHAN, SHAM-YUEN,KELSEY, WILLIAM,YEE, HELENA
申请号:
HU0200558
公开号:
HU228489B1
申请日:
1999.12.08
申请国别(地区):
HU
年份:
2013
代理人:
摘要:
This invention describes a protein-free production process for proteins having factor VIII procoagulant activity. The process includes the derivation of stable human cell clones with high productivity for B-domain deleted Factor VIII, and (2) the adaptation of cells to grow in a medium free of plasma-derived proteins.