Anke Johanna Marina Tijsen;Esther Elisa Johanna Maria Creemers;Yigal Martin Pinto
发明人:
Esther Elisa Johanna Maria Creemers,Yigal Martin Pinto,Anke Johanna Marina Tijsen
申请号：
US13263976
公开号：
US20120115929A1
申请日:
2010.04.29
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to a method for diagnosing and/or prognosing heart failure in a subject the method comprising the step of determining the level of at least one genetic marker in a body fluid sample obtained from said subject, wherein said at least one genetic marker is an mi RNA. The invention further relates to a method for treating or preventing heart failure in a subject the method comprising the step of decreasing within said subject the expression, amount, and/or activity of at least one mi RNA, or decreasing within said subject the interaction of at least one mi RNA with its m RNA target or increasing within said subject the expression, amount, and/or activity of the m RNA target of at least one mi RNA.
