BOEHRINGER INGELHEIM INTERNATIONAL GMBH;BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG
发明人:
SCHMELZER, CHRISTEL,FROEMDER, ARNE
申请号：
EP05761637.7
公开号：
EP1809243B8
申请日:
2005.06.25
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
A propellant-containing aerosol suspension (S1) comprises particles of active substance with chemically bound water, at least a propellant gas or a propellant gas mixture with TG 227 ea (1,1,1,2,3,3,3-heptafluoropropane) and/or TG 134 a (1,1,1,2-tetrafluoroethane) (85 wt.%) or in mixture with at least one other propellant gas. (S1) Contains additional free water in addition to the water chemically bound to the active substance. A propellant-containing aerosol suspension (S1) comprises particles of active substance with chemically bound water, at least a propellant gas or a propellant gas mixture with TG 227 ea (1,1,1,2,3,3,3-heptafluoropropane) and/or TG 134 a (1,1,1,2-tetrafluoroethane) (85 wt.%) or in mixture with at least one other propellant gas selected from propane, butane, pentane, dimethylether, difluorochloromethane, difluoromethane, 2,2,2 trifluoroethane, isobutane, isopentane and neopentane. (S1) Contains additional free water in addition to the water chemically bound to the active substance. Independent claims are included for: (1) preparing (S1) involving adding water to an anhydrous propellant gas or propellant gas mixture； and (2) a container containing (S1) and a suitable valve that is adjusted before use in relation to its water content. - ACTIVITY : Antiasthmatic； Respiratory-Gen.； CNS-Gen.； Analgesic； Antimigraine； Hypotensive； Vasotropic. No suitable data given. - MECHANISM OF ACTION : None given.
