The present invention provides a use of a flavonoid in manufacturing a composition for wound healing, preferably a non-glycosylated flavone. Particularly, the present invention is directed to the use in treating skin disorders such as trauma, burns, chronic wounds, especially a wound healing in diabetic patient.本發明提供一種類黃酮化合物用於製備傷口癒合組合物之用途,其中該化合物較佳為非糖基化黃酮。特定而言,本發明用途可用於治療外傷、燒燙傷及慢性傷口之皮膚症狀,尤指糖尿病患者傷口之癒合。