Daqing Sun;Lisa Julian;Felix Gonzalez Lopez De Turiso;Jay P. Powers;Xuelei Yan
发明人:
Jay P. Powers,Daqing Sun,Xuelei Yan,Lisa Julian,Felix Gonzalez Lopez De Turiso
申请号:
US12664137
公开号:
US08765788B2
申请日:
2008.06.11
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides tricyclic compounds according to formula (I): (I) where R1, R2, R3, W, X, Y, Z, m, n, and p are as defined in the description; as well as pharmaceutical compositions comprising the same, methods of use of the compounds and compositions of the invention for the treatment of conditions associated with hydroxysteroid dehydrogenases (e.g., 11-HSD1), and the use of the compounds of the invention in the preparation of medicaments for the treatment of hydroxysteroid dehydrogenase-associated conditions.