Provided herein are new compositions, methods, and devices to treat cancer through a combination of immunologic chemotherapeutic agents and ablation techniques. These compositions can include immune checkpoint inhibitors, cytokines and nucleic acid drugs that aid in eliciting an immune response to treat the tumor. The administration of these compositions in addition to various ablating techniques provides a presentation of the cancer cell antigens to the immune system and the immunologic targeting of the cancer.本文提供透過免疫化學治療劑與消融(ablation)技術的組合來治療癌症的新穎組合物、方法以及裝置。這些組合物可包括有助於引起免疫反應來治療腫瘤的免疫查核點抑制劑、細胞介素與核酸藥物。除了各種消融技術外,投予此等組合物提供癌細胞抗原呈遞至免疫系統和癌症的免疫靶向。