PURPOSE: A composition for promoting human mesenchymal stem cell differentiation is provided to enhance skin volume and elasticity and to improve anti-wrinkling.CONSTITUTION: An external use skin composition for promoting adipocytes contains 0.0001-30 wt% of Artemisia asiatica extract as an active ingredient. The composition promotes differentiation of mesenchymal stem cells into adipocytes. The mesenchymal stem cells are derived from human body. A pharmaceutical composition for promoting differentiation into adipocytes contains the extract as an active ingredient. The dose of the extract is 0.001 mg/kg/day-2,000 mg/kg/day.COPYRIGHT KIPO 2012본 발명은 인간 중간엽줄기세포의 분화 촉진용 조성물에 관한 것으로, 보다 상세하게는 애엽 추출물을 유효성분으로 함유하여 인간 중간엽줄기세포를 지방세포로 분화하는 것을 촉진시킴으로써 지방체를 생성하여 피부의 볼륨과 탄력을 증진시키고 주름을 개선시키는 인간 중간엽줄기세포의 분화 촉진용 조성물에 관한 것이다.
