The nucleic acid of the Amino acid sequence of the C- end parts in the CH4- structures domain of the C- end parts or IgE or IgM Class immunoglobulins in the bright CH3- structures domains comprising Knitting Code IgA or IgG Class immunoglobulins this Hair, wherein including Gly-From amino acids ,-Er Tai Department in the Amino acid sequence of the C- end parts in The CH3- or CH4- structures domain by nucleic acid ggaaaa or nucleic acid ggcaaa or nucleic acid gggaaa or nucleic acid gggaag or nucleic acid ggcaag or nucleic acid ggaaag Knitting Code.本發明包含編碼IgA或IgG類免疫球蛋白之CH3-結構域之C-端部分、或IgE或IgM類免疫球蛋白之CH4-結構域之C-端部分的胺基酸序列的核酸,其中包含在該CH3-或CH4-結構域之C-端部分的胺基酸序列中之甘胺酸-離胺酸-二肽係由核酸ggaaaa、或核酸ggcaaa、或核酸gggaaa、或核酸gggaag、或核酸ggcaag、或核酸ggaaag編碼。