The present invention relates to recombinant measles virus expressing proteins of a Plasmodium parasite and their applications, in particular in inducing preventive protection against a Plasmodium infection. The present invention is directed to recombinant measles virus (MV) expressing (i) at least the circumsporozoite (CS) protein of a Plasmodium parasite or an antigenic fragment thereof, and at least a chimeric antigen of a Plasmodium parasite as defined below, or (ii) at least the CS protein of a Plasmodium parasite or an antigenic fragment thereof, at least a chimeric antigen of a Plasmodium parasite as defined below and at least the reticulocyte-binding protein homologue 5 (RH5) of a Plasmodium parasite or an antigenic fragment thereof, and concerns recombinant infectious virus particles of said MV- malaria able to replicate in a host after an administration. The present invention provides means, in particular nucleic acids, vectors, cells and rescue systems to produce these recombinant infectious virus particles. The present invention also relates to the use of these recombinant infectious virus particles, in particular under the form of a composition, more particularly in a vaccine composition, for the prevention of a Plasmodium infection or for the preventive protection against clinical outcomes of infection by a Plasmodium parasite.La présente invention concerne des protéines d'un parasite Plasmodium qui expriment le virus de la rougeole recombinant exprimant et leurs applications, en particulier pour induire une protection préventive contre une infection à Plasmodium. La présente invention concerne le virus de la rougeole recombinant (MV) exprimant (i) au moins la protéine circumsporozoïte (CS) d'un parasite Plasmodium ou d'un fragment antigénique de celui-ci, et au moins un antigène chimère d'un parasite Plasmodium tel que défini ci-dessous, ou (ii) au moins la protéine CS d'un parasite Plasmodium ou d'un fragment antigénique de celui-ci, au moins un anti
