PEPTIDE REAGENTS AND METHODS FOR DETECTION AND TARGETING OF DYSPLASIA, EARLY CANCER AND CANCER

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专利权人:

THE REGENTS OF THE UNIVERSITY OF MICHIGAN

发明人:

Thomas D. Wang,Juan Zhou,Bishnu P. Joshi

申请号：

US15505846

公开号：

US20170246324A1

申请日:

2015.08.21

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The present invention is directed to EGFR-specific peptide reagents, methods for detecting pre-cancer, early cancer and/or cancer using the peptide reagents, and methods for targeting pre-cancer cells, early cancer cells and/or cancer cells using the peptide reagents. In one aspect, the disclosure provides reagents consisting essentially of a peptide QRHKPRE (SEQ ID NO: 1), HAHRSWS (SEQ ID NO: 2), YLTMPTP (SEQ ID NO: 3), TYPISFM (SEQ ID NO: 4), KLPGWSG (SEQ ID NO: 5), IQSPHFF (SEQ ID NO: 6), YSIPKSS (SEQ ID NO: 7), SHRNRPRNTQPS (SEQ ID NO: 8), NRHKPREKTFTD (SEQ ID NO: 9).

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http://www.ckcest.cn/home/