鱼卵细胞提取物及其在诱导人成体细胞分化为多能干细胞中的应用
- 专利权人:
- 成都军区昆明总医院;潘兴华
- 发明人:
- 潘兴华,朱向情
- 申请号:
- CN200910094054.8
- 公开号:
- CN101481679A
- 申请日:
- 2009.01.22
- 申请国别(地区):
- 中国
- 年份:
- 2009
- 代理人:
- 苏 梅
- 摘要:
- 本发明公开一种鱼卵细胞提取物及其在诱导人成体细胞分化为多能干细胞中的应用。杀鱼取卵,经过冻融,离心,过滤、蛋白浓度4毫克/毫升,为卵细胞提取物。从成人全身各个组织获取成熟的体细胞原代细胞或传代二至四后代细胞,用本发明的提取物来诱导成体细胞,使其逆向分化为多能性干细胞,可以为临床提供各种细胞来源,还可以用来治疗各种疾病。与现有技术相比具有不损伤细胞、培养条件简单、无毒、诱导效率高等优点,同时也避免利用基因重组技术存在的安全隐患。
- 来源网站:
- 中国工程科技知识中心
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