A body-worn physiological sensor assembly (100) having a monitor/event recorder (120), a plurality of ECG electrodes (140, 180, 182), and an interconnect device (160) disposed between the recorder and the ECG electrodes. The interconnect device is preferably disposable, and simplifies the cleaning and decontamination of the assembly after use. In addition, the disposable interconnect device (160) incorporates the primary wear surfaces for the various electrical connections.