Pawel DRAPALA;Hans Hitz;Bin JIANG;Rolf Schaefer;Jennifer J. KANG-MIELER;Eric BREY;Victor PEREZ-LUNA
发明人:
Jennifer J. KANG-MIELER,Eric BREY,Victor PEREZ-LUNA,Bin JIANG,Pawel DRAPALA,Hans Hitz,Rolf Schaefer
申请号：
US13045643
公开号：
US20120231072A1
申请日:
2011.03.11
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A thermo-responsive hydrogel, including a biocompatible monomer and/or polymer having an amino acid side chain. The hydrogel is thermo-responsive at a physiological temperature, and can include, incorporate, or encapsulate a treatment agent, such as a drug composition, a biomolecule, and/or a nanoparticle. The hydrogel is useful in delivering the treatment agent. The hydrogel is in a first physicochemical state for administration to a mammal. The hydrogel is thermo-responsive at a physiological temperature of the mammal, and changes to a second physicochemical state that is more solid than the first physicochemical state. In the second physicochemical state the thermo-responsive hydrogel releases the treatment agent.
