Adjei, Akwete L.,Chen, Sibao,Kupper, Robert Joe,Mancinelli, Vincent
申请号：
AU2013203493
公开号：
AU2013203493A1
申请日:
2013.03.01
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
#$%^&*AU2013203493A120130919.pdf#####- 98 ABSTRACT [00201] Disclosed in certain embodiments is an immediate release solid oral dosage form comprising a plurality of particles, each particle comprising: (i) a core comprising a first active agent (ii) a coating comprising a second active agent layered over the core and (iii) a material that is sensitive to acidic pH layered over the coated core wherein the dosage form releases at least about 70% of the second active agent within 45 minutes as measured by in-vitro dissolution in a USP Apparatus 2 (paddle) at 50 rpm in 500 ml 0.1N HCl at 370 C.
