The present invention provides compositions containing (i) a pharmaceuticallyactive agent selected from a group consisting of an arylcycloalkyamine or aderivative, analogue or pharmaceutically active salt thereof, and (ii) abiocompatible polymer or a combination of biocompatible polymers. Thesecompositions or medicaments containing these compositions may be used for theprevention and/or treatment of inner ear diseases, e.g. tinnitus.