A method system and computer-readable medium for detecting a disease of a prostate. Exemplary embodiments of the present disclosure can include receiving an image dataset acquired with at least one acquisition mode segmenting a region of interest including the prostate from the dataset applying conformal mapping to map the region of interest to a canonical shape generating a 3D visualization of the prostate using the canonically mapped dataset and applying computer aided detection (CAD) to the canonically mapped volume to detect a region of disease of the organ. (Fig. 2)