您的位置: 首页 > 农业专利 > 详情页

FINE DISPERSION OF SPARINGLY SOLUBLE DRUG AND PROCESS FOR PRODUCING THE SAME
专利权人:
Toyama Chemical Co.; Ltd.
发明人:
KUBO Yoshiko,KUBO Yoshiko,YAMAKAWA Tetsumi,YAMAKAWA Tetsumi,YAMASAKI Yasuomi,YAMASAKI Yasuomi
申请号:
SI200532064
公开号:
SI1731138T1
申请日:
2005.03.28
申请国别(地区):
SI
年份:
2016
代理人:
摘要:
An effective and simple process for producing a fine dispersion of a poorly soluble drug and a fine sparingly-soluble-drug dispersion having excellent dispersion stability. In a first step, a poorly soluble drug is suspended in a liquid containing no deflocculant and the suspension is subjected to a high-pressure treatment with a high-pressure homogenizer. In a second step, a deflocculant is added to the dispersion obtained in the first step and this dispersion is subjected to a deagglomeration treatment such as a high-pressure treatment with a high-pressure homogenizer or an ultrasonic treatment. Thus, a fine dispersion of the poorly soluble drug is effectively and simply produced in which the size of the particles dispersed is on the order of nanometer. The fine sparingly-soluble-drug dispersion produced has excellent dispersion stability and the fine particles of the poorly soluble drug do not suffer aggregation/sedimentation even upon standing. Also provided is an excellent medicinal preparation reduced in the content of contaminants. It is obtained from the thus-produced fine dispersion of the poorly soluble drug.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充