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METHOD FOR INCREASING THE GROWTH SPEED OF NEWBORN CHILDREN
专利权人:
СВЕДИШ ОРФАН БИОВИТРУМ АБ (ПАБЛ) (SE)
发明人:
ХЕРНЕЛЛЬ Олле (SE),СТРЕМБЕРГ Патрик (SE),СВЕНССОН Леннарт (SE),ТИМДАХЛЬ Кристина (SE),ВОГЕРЕ Мортен (SE),ЭМАН Мария (SE),ОЛЬССОН Биргитта (SE)
申请号:
RU2013123053/15
公开号:
RU2013123053A
申请日:
2010.10.21
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. Recombinant bile salt stimulated human lipase (rhBSSL) for use in the method of increasing the growth rate of a newborn baby, said method comprising the step of enteral administration of a recombinant bile salt stimulated human lipase to said newborn, wherein said lipase is administered in an amount of 1 day up to 100 mg of the specified lipase per kilogram of body weight of the newborn, from 5 to 50 mg of the specified lipase per kilogram of mass of the newborn, or from 15 to 40 mg of the specified lipase per kilogram m ssy novorozhdennogo.2. Recombinant bile salt stimulated human lipase (rhBSSL) for use in the method: (X) protecting the mucosa of the small intestine of a newborn baby from damage; (Y) protecting the immature intestinal epithelium of the newborn from the harmful effects of incompletely digested and / or excess fat and / or lipid; and / or (Z) restricting the accumulation of incompletely digested and / or excess fat and / or lipid in the ileum of the newborn; however, in each case, the specified method includes the stage of enteral administration of recombinant stimulated bile salts of human lipase to the specified newborn. RhBSSL for use according to claim 2, wherein administering said lipase protects the mucous membrane of the small intestine from the harmful effects of incompletely digested or excess fat and / or lipid. RhBSSL for use according to claim 2 or 3, in which the introduction of the specified lipase protects the mucous membrane of the jejunum and / or ileum of the specified newborn from damage. RhBSSL for use according to claim 2, in which the introduction of the specified lipases1. Рекомбинантная стимулируемая желчными солями липаза человека (rhBSSL) для применения в способе увеличения скорости роста новорожденного ребенка, при этом указанный способ включает стадию энтерального введения рекомбинантной стимулируемой желчными солями липазы человека указанному новорожденному, где указанную липазу вводят в количестве, составляющем в ден
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