The present invention relates to a kind of Noninvasive sensing system of concentration for the substance in measurement object, system includes: support device, which is suitable for being placed as the surface near or against object First transmission antenna, which is mounted in support device or in support device, for sending ELECTROMAGNETIC RADIATION SIGNATURE in object And second receiving antenna, second receiving antenna is mounted in support device or in support device, and it is adjacent with the first transmission antenna, for receive be reflected back to by support device covering object same surface ELECTROMAGNETIC RADIATION SIGNATURE at least part, the ELECTROMAGNETIC RADIATION SIGNATURE due to the matter interaction in measured object and reflected.