This disclosure relates to compositions comprising a vehicle such as a polymer base, moringa oil and neem oil. The combination of the two oils is in an amount sufficient to prevent the establishment or proliferation of a microorganism, such as a mildew, on the surface of an inanimate object. The moringa oil and neem oil combination can be advantageously admixed with a paint base, a solvent system, or other vehicle base for the treatment of wood, dry wall, or other porous or non-porous surface that is susceptible to a biological infestation.