Marius Wernig,Thomas C. Sudhof,Thomas Vierbuchen,Austin Ostermeier,Zhiping Pang
申请号:
US13522002
公开号:
US20130022583A1
申请日:
2011.01.19
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Methods, compositions and kits for producing functional neurons, astroctyes, oligodendrocytes and progenitor cells thereof are provided. These methods, compositions and kits find use in producing neurons, astrocytes, oligodendrocytes, and progenitor cells thereof for transplantation, for experimental evaluation, as a source of lineage- and cell-specific products, and the like, for example for use in treating human disorders of the CNS. Also provided are methods, compositions and kits for screening candidate agents for activity in converting cells into neuronal cells, astrocytes, oligodendrocytes, and progenitor cells thereof.