The present invention relates to a composition for treatment of cartilage damage including degenerative arthritis and, specifically, to a pharmaceutical composition for bone diseases, wherein the composition contains the stromal vascular fraction (SVF) and the extracellular matrix (ECM) and enables bone generation without side effects to minimize the surgical operation, such as incision, leading to no scars and a quick recovery. In addition, the treatment for cartilage damage including degenerative arthritis can be effectively performed by adding platelet rich plasma (PRP), an aqueous solution of calcium chloride (CaCl2), and hyaluronic acid to the composition.La présente invention concerne une composition pour le traitement de lésions cartilagineuses, notamment de larthrose et, plus particulièrement, une composition pharmaceutique pour des maladies osseuses, ladite composition contenant la fraction stroma-vasculaire (FSV) et la matrice extracellulaire (MEC) et permettant une génération osseuse sans effets secondaires afin de réduire au minimum lopération chirurgicale, telle quune incision, conduisant ainsi à aucune cicatrice et à une récupération rapide. De plus, le traitement de lésions cartilagineuses, notamment de larthrose, peut être effectué efficacement par lajout, dans la composition, dun plasma riche en plaquettes (PRP), dune solution aqueuse de chlorure de calcium (CaCl2) et dacide hyaluronique.본 발명은 퇴행성 관절염을 포함하는 연골손상 치료용 조성물에 관한 것으로, 기질혈관분획 (SVF, stromal vascular fraction), 세포외기질 (ECM, extra cellular matrix)을 포함하며, 부작용없이 뼈의 재생이 가능하여 절개 등의 외과적 수술을 최소화할 수 있어 흉터가 없고 회복이 빠른 장점이 있는 뼈 질환용 약학 조성물에 관한 것이다. 또한 상기 조성물에 혈소판 풍부 혈장 (PRP, platelet rich plasma)과 염화칼슘수용액 (CaCl2) 및 히알루론산 (hyaluroni c acid)을 추가함으로써, 퇴행성 관절염을 포함하는 연골손상에 대한 치료를 효과적으로 수행할 수 있다.