Yat Sun Or,Ruichao Shen,Xuechao Xing,Brett Granger,Bin Wang,Jun Ma,Jing He,Yong He,Jiang Long,Guoqiang Wang
申请号:
US15497307
公开号:
US20170304271A1
申请日:
2017.04.26
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides compounds of Formula I,pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated as FXR modulators. Specifically, the present invention relates to isoxazole derivatives useful as agonists for FXR, and methods for their preparation and use.