An assembly for disinfecting a female port of a medical implement is provided. The assembly includes a receiving portion and a disinfecting member disposed substantially inside the receiving portion. The receiving portion includes an open proximal end, a side wall, and a syringe tip having an external surface. An internal surface has a plurality of protrusions disposed near the open proximal end. The syringe tip includes a passageway therethrough in a fluid communication with the chamber and an external surface extending towards the open proximal end so as to create a cavity between the internal surface of the side wall and the external surface of the syringe tip. The protrusions are shaped to engage helical threads of the female port of a medical implement. The second disinfecting member is disposed substantially inside the cavity created by the protrusions of the internal surface and the external surface of the syringe tip.