HEAT SHOCK PROTEIN BINDING COMPOUNDS, COMPOSITIONS, AND METHODS FOR MAKING AND USING SAME
- 专利权人:
- 发明人:
- CHIOSIS GABRIELA,TALDONE TONY,RODINA ANNA,PATEL PALLAV,KANG YANLONG
- 申请号:
- IN2281/CHENP/2012
- 公开号:
- IN2012CN02281A
- 申请日:
- 2012.03.13
- 申请国别(地区):
- IN
- 年份:
- 2012
- 代理人:
- 摘要:
The present subject matter relates to a compound represented by the general formula (I) or (I) or a pharmacologically acceptable salt thereof pharmaceutical compositions containing at least one of these compounds methods of making at least one of these compounds methods of using at least one of these compounds for treating and/or preventing various cancers and/or proliferation disorders methods of using at least one of these compounds for monitoring the effectiveness of an anticancer therapy against various cancers. In one embodiment, the subject matter relates to compounds that bind with a level of specificity to heat shock protein 70 (Hsp70). In another embodiment, the subject matter relates to compounds that bind with a level of specificity to inhibit both heat shock protein 70 (Hsp70) and heat shock cognate protein 70 (Hsc70).
[WO2011022440A2]
- 来源网站:
- 中国工程科技知识中心
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