LANGEDIJK, JOHANNES PETRUS MARIA,RUTTEN, LUCY,STROKAPPE, NIKA MINDY,TRUAN, DAPHNE
申请号：
CA3069052
公开号：
CA3069052A1
申请日:
2018.07.12
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
Human immunodeficiency virus (HIV) envelope proteins having specified mutations that stabilize the trimeric form of the envelope protein are provided. The HIV envelope proteins described herein have an improved percentage of trimer formation and/or an improved trimer yield. Also provided are particles displaying the HIV envelope proteins, nucleic acid molecules and vectors encoding the HIV envelope proteins, as well as compositions containing the HIV envelope proteins, particles, nucleic acid, or vectors.
