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Unacylated ghrelin and analogs as therapeutic agents for vascular remodeling in diabetic patients and treatment of cardiovascular disease
专利权人:
Alize Pharma SAS
发明人:
Muccioli, Giampiero,Brizzi, Maria Felice,Ghigo, Ezio
申请号:
AU2009256558
公开号:
AU2009256558B2
申请日:
2009.06.12
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention relates to a method for treating a cardiovascular disease, for increasing the number of circulating angiogenic cells (CAC) and/or improving the function of CAC and a method for improving vascular remodeling and/or neovascularisation. The method comprises administering to the subject a therapeutically effective amount of unacylated ghrelin or a polypeptide comprising the amino acid sequence set forth in SEQ ID NO: 1 or a fragment or analog thereof having the biological activity of SEQ ID NO: 1; and to pharmaceutical compositions comprising unacylated ghrelin or a polypeptide comprising the amino acid sequence set forth in SEQ ID NO: 1 or a fragment or analog thereof having the biological activity of SEQ ID NO: 1.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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