Anti-cd38 antibody and lenalidomide or bortezomib for the treatment of multiple myeloma and nhl

• 收藏
• 分享

专利权人:

MORPHOSYS AG

发明人:

ROJKJAER LISA,BOXHAMMER RAINER,ENDELL JAN,WINDERLICH MARK,SAMUELSSON CHRISTOFER

申请号：

NZ60747311

公开号：

NZ607473A

申请日:

2011.09.26

申请国别(地区):

NZ

年份:

2014

代理人:

摘要：

Disclosed is a composition comprising an antibody specific for CD38 comprising an HCDR1 region of sequence SYYMN (SEQ ID NO: 14), an HCDR2 region of sequence GISGDPSNTYYADSVKG (SEQ ID NO: 2), an HCDR3 of sequence DLPLVYTGFAY (SEQ ID NO: 3), an LCDR1 region of sequence SGDNLRHYYVY (SEQ ID NO: 4), an LCDR2 region of sequence GDSKRPS (SEQ ID NO: 5), and an LCDR3 region of sequence QTYTGGASL (SEQ ID NO: 6)； and either (a) thalidomide, a thalidomide analogue, lenalidomide, or pomalidomide, or (b) bortezomib, for use in the treatment of multiple myeloma and/or non-hodgkins lymphoma.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/