DOMAINE EXTRACELLULAIRE DE SOUS-UNITE ALPHA DU RECEPTEUR FC IGE, COMPOSITION PHARMACEUTIQUE LE COMPRENANT ET SON PROCEDE DE PRODUCTION

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专利权人:

INC.;GI INNOVATION

发明人:

SUNG, YOUNG CHUL,YANG, ZUNGYOON

申请号：

CA3086222

公开号：

CA3086222A1

申请日:

2019.01.08

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The present invention provides a polypeptide protein dimer comprising two monomers comprising an extracellular domain of an alpha subunit of an IgE Fc receptor (FceRIa-ECD). The protein dimer according to the present invention is excellent in IgE binding ability and lacks ADCC and CDC functions when compared with a conventional therapeutic agent comprising an anti-IgE antibody, and has an advantage of fewer other side effects, and therefore, the protein dimer may be applied to medicine for therapeutic or prophylactic use against allergic diseases mediated by IgE.

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中国工程科技知识中心

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http://www.ckcest.cn/home/