An exemplary orthopedic adjustment device includes an orthopedic appliance, an adjustment unit module and a pressure control module. The appliance is configured for supporting a human spine. The adjustment unit module includes adjustment units. Each of the adjustment units includes a chamber, a pressure sensor and a pump. The pressure sensor and the pump are arranged in the chamber. Each of the pressure sensors is configured for detecting a pressure of each chamber corresponding thereto. Each of the pumps is configured for adjusting the pressure of each chamber corresponding thereto. The pressure control module is configured for receiving pressure signals from the pressure sensors of the chambers and providing pressure adjusting signals to the pumps to adjust the pressures of the chambers.
