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Abuse resistant pharmaceutical compositions
专利权人:
Recro Gainesville LLC
发明人:
Rekhi, Gurvinder Singh,Sidwell, Richard
申请号:
AU2015313785
公开号:
AU2015313785A1
申请日:
2015.09.11
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The present invention relates to a composition comprising pharmaceutical active ingredients which are susceptible to, or have potential for, abuse. The invention provides an oral pharmaceutical composition comprising a first population of beads and a second population of beads. The first bead population comprises a pharmaceutically active ingredient susceptible to, or having the potential for, abuse. The second bead population comprises a gelling agent and a coating substantially surrounding the gelling agent, but containing no pharmaceutically active ingredient. The first bead population and the second bead population are physically separable, but visually indistinguishable to the naked eye. Upon ingress of water into the second population of beads, the gelling agent is caused to swell forming a viscous mass inhibiting or preventing the extraction of the active ingredient.
来源网站:
中国工程科技知识中心
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