Oivin M. Guicherit;Shirley Ann Brunton;Lawrence I. Kruse
发明人:
Shirley Ann Brunton,Oivin M. Guicherit,Lawrence I. Kruse
申请号：
US13492459
公开号：
US20120245184A1
申请日:
2012.06.08
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention makes available methods and reagents for modulating proliferation or differentiation in a cell or tissue comprising contacting the cell with a compound. In certain embodiments, the methods and reagents may be employed to correct or inhibit an aberrant or unwanted growth state, e.g., by antagonizing a normal patched pathway or agonizing smoothened or hedgehog activity.
