The present invention relates to glucommannan oligosaccharides and polysaccharidesthat possess one or more properties selected from skin regeneration, wound healingand skin augmentation. More particularly, the invention relates to the use ofglucomannan oligosaccharides and polysaccharides for one or more of skin regeneration,wound healing and skin augmentation agents in a mammal. The invention also relatesto a pharmaceutical formulation for treating skin of a subject comprising anactive component comprising glucomannan in a suitable diluent, excipient orphysical form such as dermal scaffold or sponge, the active component being capableof promoting an accumulation of fibroblasts in the skin and stimulating productionof collagen in the skin.