The Trustees of the University of Pennsylvania;Ritis Konstantinos
发明人:
Lambris, John D.,Ritis, Konstantinos
申请号:
AU2009298684
公开号:
AU2009298684B2
申请日:
2009.09.29
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
Methods for reducing or eliminating biomaterial-induced procoagulant activity in blood subjected to extracorporeal treatment that exposes the blood to the biomaterial are disclosed. The methods involve treatment of the blood, or the extracorporeal biomaterial, or both, with a complement inhibitor to inhibit C5a/C5aR-mediated tissue factor formation in the blood.