An imaging guidewire having at its distal tip at least a first Imaging sensor of a forward looking imaging system directed towards an area to be treated and configured to provide imaging data to a processing system, an optical imaging system directed towards an area that has already been treated and configured to provide imaging data of a treated area to the image processing system and at least one display device for displaying images processed by the image processing system. Operating the imaging guidewire during a medical procedure includes the steps of: Generating an image of an area to be treated Upon completion of at least a portion of the medical treatment, generating an image of an area that has been treated and displaying at least the first and second images wherein each one of the first and second images can be generated by one or more imaging modalities.
