TODA MARIHIRO,SHIDA TAKESHI,IWAMOTO MITSUHIRO,YAMAZAKI MAMI,TAKANO RIEKO,KATAGIRI TAKAHIRO,ASHIDA SHINJI
申请号：
ZA201301652
公开号：
ZA201301652B
申请日:
2013.03.04
申请国别(地区):
ZA
年份:
2014
代理人:
摘要：
To find a therapeutic and/or prophylactic agent for gastrointestinal disorders and so on, the agent having excellent activity and high safety. A compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof. In the formula, A represents an optionally substituted phenylene group； B represents an optionally substituted 4- to 10-membered heterocyclic group, an optionally substituted C6-C10 aryl group, or an optionally substituted C3-C10 cycloalkyl group； R 1 represents a hydrogen atom or a C1-C3 alkyl group； R 2 represents a hydrogen atom or a C1-C3 alkyl group； R 3 represents a C1-C6 alkyl group, a C3-C10 cycloalkyl group, a C1-C3 alkoxy C1-C3 alkyl group, or a C1-C3 hydroxyalkyl group； R 4 represents a hydrogen atom, a C1-C6 alkyl group, or a halogen atom； n represents an integer of 1 to 4； and X represents methylene, -O-, -NH-, -N(C1-C3 alkyl)-, -C(=O)-, -S-, -S(O)-, -S(O 2 )- or a single bond.
