Deborah M. Schachter;Yufu Li;Qiang Zhang;Peter Van Remoortere
发明人:
Deborah M. Schachter,Qiang Zhang,Peter Van Remoortere,Yufu Li
申请号:
US12963012
公开号:
US20120148678A1
申请日:
2010.12.08
申请国别(地区):
US
年份:
2012
代理人:
摘要:
We have disclosed an implantable sustained release composition comprising, a biocompatible, biodegradable polymer, a cyclodextrin inclusion complex of a poorly water soluble pharmaceutical agent present, and a plasticizer, where the polymer is the minority phase of the formulation. Furthermore, The we disclose an implantable sustained release composition that provides a detectable plasma level of an otherwise poorly soluble drug for at least 28 days.