MEIER, Daniel, J.,SANDOVAL, Ruben, M., Jr.,REILLY, Erinn
申请号：
EP16815412
公开号：
EP3313286A4
申请日:
2016.06.24
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Disclosed are methods for determining biometric indicators such as plasma volume, hematocrit and glomerular filtration rate, in mammalian subjects such as humans. The methods utilize a plurality of fluorescent tags having distinct fluorescent characteristics, which may be associated with a single static molecule, or wherein the static molecule is labeled with a fluorescent tag and a dynamic molecule is labeled with another fluorescent tag. One or more measurements of the intensities of the fluorescent emissions are taken subsequent to introduction of an injectate which contains the fluorescent tags, which can be taken using a probe or via a blood or plasma sample. Compositions and apparatuses for practicing the methods are also disclosed.
