THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
发明人:
CHENG, JIANJUN,LU, HUA
申请号：
EP11845856
公开号：
EP2646048A4
申请日:
2011.11.30
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
The invention provides polymers comprising Formula I: wherein monomer is a repeating unit comprising 2, 3, 4, 5, 6 or 7 carbon atoms and the monomers are linked together through amide or ester bonds n is about 6 to about 1000 and Linker is an optionally substituted carbon chain that is optionally interrupted by moieties such as oxygen, nitrogen, sulfur, phosphorus, or silicon. Charge is a moiety having a positive or negative charge on a heteroatom, such as nitrogen, oxygen, phosphorus, or sulfur where the Linker separates the monomer and the Charge by at least six linear atoms. The invention also provides methods of preparing the polymers and the copolymers and methods of using the polymers and copolymers, for example, as drug delivery systems, as membrane penetrating peptides, and as therapeutic agents.
