The invention relates to a transcranial electrostimulation device for treating different illnesses. In an exemplary embodiment, the transcranial electrostimulation device includes a bipolar pulse source for generating an electrical current and a patient physiological status processor that provides a biofeedback mechanism for adjusting the applied electrical stimulation. The device further includes electrodes positioned on a patients skin at a retro-mastoidal location for delivering bipolar electrical pulses to induce transcranial electrostimulation.