ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC.;COA THERAPEUTICS, INC.
发明人:
LEE, Richard,TANGALLAPALLY, Rajendra,ROCK, Charles,JACKOWSKI, Suzanne,EDWARDS, Anne,YUN, Mi,SUBRAMANIAN, Chitra,ZAMBONI, Robert,REDDY, T.
申请号:
SG11202006047R
公开号:
SG11202006047RA
申请日:
2018.12.26
申请国别(地区):
SG
年份:
2020
代理人:
摘要:
The present disclosure relates to chemical compounds that modulate pantothenate kinase (PanK) activity for the treatment of metabolic disorders (such as diabetes mellitus type II), neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.