VAN EENENNAAM HANS,VAN ELSAS ANDREA,MEDEMA JAN PAUL,LUTJE HULSIK DAVID
申请号：
IN201727028124
公开号：
IN201727028124A
申请日:
2017.08.08
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
H L The disclosure relates to APRIL binding antibodies which bind the same epitope of human APRIL as an antibody having an antigen binding site of hAPRIL.01A. The antibodies of the present disclosure comprise specific selections of framework sequences of the Vand Vdomains and have unexpected features in comparison to hAPRIL.01A. The disclosure further relates to compositions comprising an antibody of the invention and to the medical and diagnostic uses of the antibodies and compositions.
