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Compound having 11β-HSD1 inhibitory activity
专利权人:
Ryo Suzuki
发明人:
Ryo Suzuki,Ayako Mikami,Hiroaki Tanaka,Hiroshi Fukushima
申请号:
US12666802
公开号:
US08222417B2
申请日:
2008.06.24
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides compounds having excellent 11β-HSD1 inhibitory activity.A compound represented by the following formula (I):[whereinX1 represents an oxygen atom, or the formula —(CR11R12)p—, etc.,Y1 represents a hydrogen atom, a hydroxyl group, etc.,Z1 represents an oxygen atom or the formula —(NR14)—,R1 represents a hydrogen atom, a halogen atom, a cyano group, a C1-4 alkyl group, a C1-4 alkyl group substituted with 1 to 3 halogen atoms, a C1-4 alkoxy group, a C1-4 alkoxycarbonyl group, a carboxyl group, a carbamoyl group, or an amino group, and m represents an integer of 1 or 2, andR2 represents a hydrogen atom or a C1-4 alkyl group, and n represents an integer of 1 or 2].
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