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DRUG DELIVERY CONJUGATES FOR TREATING RESISTANT CANCER AND FOR USE IN COMBINATION THERAPY
专利权人:
ENDOCYTE; INC.
发明人:
VLAHOV, IONTCHO RADOSLAVOV,LEAMON, CHRISTOPHER PAUL,REDDY, JOSEPH ANAND
申请号:
CA2945367
公开号:
CA2945367A1
申请日:
2015.04.14
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Described herein are drug delivery conjugates for targeted therapy. In particular, described herein are drug delivery conjugates that include polyvalent linkers comprising one or more unnatural amino acids that are useful for treating cancers and inflammatory diseases. In some embodiments, the cancer is selected from the group consisting of a carcinoma, a sarcoma, a lymphoma, Hodgekins disease, a melanoma, a mesothelioma, Burkitfs lymphoma, a nasopharyngeal carcinoma, a leukemia, and a myeloma.
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