Isoxazole derivative as mutated isocitrate dehydrogenase 1 inhibitor

• 收藏
• 分享

专利权人:

Limited;National Cancer Center;Daiichi Sankyo Company;Daiichi Sankyo Company, Limited

发明人:

Saito, Shoichi,Itoh, Masao,Fujisawa, Tetsunori,Saito, Hironao,Kiyotsuka, Yohei,Watanabe, Hideaki,Matsunaga, Hironori,Kagoshima, Yoshiko,Suzuki, Tetsuya,Ogawara, Yoko,Kitabayashi, Kazuo

申请号：

AU2015325279

公开号：

AU2015325279A1

申请日:

2015.10.01

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

It was discovered that a compound of general formula (I) that has an isoxazole skeleton has an excellent inhibitory activity on a mutated IDH1 protein, inhibits 2-HG production by the aforesaid protein and can effectively inhibit the proliferation of various tumors expressing the aforesaid protein.In general formula (I), R

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/