KOUSTUBH RANADE,BRANDON W. HIGGS,RAJIV G. RAJA,PHILIP Z. BROHAWN,HAN SI,MIKE KUZIORA
申请号：
US16710938
公开号：
US20200190598A1
申请日:
2019.12.11
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The disclosure generally relates to methods for treating non-small cell lung cancer patients based on use of blood-based tumor mutation burden to predict overall survival in patients treated with durvalumab, tremelimumab, and/or a chemotherapy agent. The disclosure also relates to methods for treating non-small cell lung cancer patients based on identification of mutations in circulating tumor DNA associated with sensitivity or resistance to immunotherapy.
